Description

(S)-2-Chloro-1-(3-Chloro-Phenyl)-Ethanol CAS NO 174699-78-6 is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. Its defined stereochemistry and functional group arrangement make it a valuable building block for the synthesis of complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Used as a precursor or chiral auxiliary in stereoselective chemical reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Serves as a building block in the synthesis of advanced chiral pesticides and herbicides, where specific stereochemistry can influence biological activity.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for use in homogeneous catalysis and enantioselective transformations.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in organic chemistry and process development.

Basic Information

Product Name	(S)-2-Chloro-1-(3-Chloro-Phenyl)-Ethanol
CAS No.	174699-78-6
Molecular Formula	C8H8Cl2O
Molecular Weight	191.05 g/mol
Synonyms	(S)-2-Chloro-1-(3-chlorophenyl)ethanol; (S)-1-(3-Chlorophenyl)-2-chloroethanol; (S)-α-Chloro-3-chlorobenzeneethanol; (S)-2-Chloro-1-(3-chlorophenyl)ethan-1-ol; (1S)-2-Chloro-1-(3-chlorophenyl)ethanol; (S)-3-Chlorophenyl chloromethyl carbinol; (S)-(-)-2-Chloro-1-(3-chlorophenyl)ethanol
EINECS	Contact for details

Quality Control

Our (S)-2-Chloro-1-(3-Chloro-Phenyl)-Ethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure it meets the high-purity standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.