Description

2-Thiophenecarboxylicacid,5-Ethynyl-(9Ci) is a specialized heterocyclic building block featuring both a carboxylic acid and an ethynyl functional group on a thiophene core. This unique bifunctional structure makes it a high-value intermediate for constructing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry, material science, and the synthesis of novel organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for conjugated polymers and organic semiconductors in OLEDs, OFETs, and solar cells.
• Chemical Research: Employed in cross-coupling reactions (e.g., Sonogashira) and click chemistry due to its reactive ethynyl group.
• Ligand and Catalyst Development: Used to create novel ligands for transition metal catalysis and organometallic complexes.

Basic Information

Item	Detail
Product Name	2-Thiophenecarboxylicacid,5-Ethynyl-(9Ci)
CAS No.	174672-58-3
Molecular Formula	C7H4O2S
Molecular Weight	152.17 g/mol
Synonyms	5-Ethynyl-2-thiophenecarboxylic acid; 5-Ethynylthiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-ethynyl-; 5-Ethynyl-2-thiophenecarboxylicacid; 5-Ethynylthiophene-2-carboxylate; 5-Ethynyl-2-carboxythiophene; 5-Ethynylthiophene-2-carboxylic acid (9CI)
EINECS	Contact for details

Quality Control

Our production of 2-Thiophenecarboxylicacid,5-Ethynyl-(9Ci) adheres to stringent internal quality protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and structural identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 aligned practices for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.