Description

2-Thiophen-2-Yl-1H-Benzoimidazole-5-Carboxylic Acid CAS NO 174422-11-8 is a high-purity, functionalized benzimidazole derivative that serves as a critical advanced intermediate in organic synthesis. This compound is valued for its unique heterocyclic structure, which combines a benzimidazole core with a thiophene moiety, making it a versatile building block for the development of novel active compounds. It is primarily sought after by research and development laboratories, as well as production facilities, in the pharmaceutical and agrochemical sectors for creating new molecules with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors where the benzimidazole-thiophene scaffold is pharmacologically active.
• Agrochemical Research: Used in the development of new fungicides, herbicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers, organic semiconductors, or ligands for metal-organic frameworks (MOFs).
• Chemical Synthesis: Employed as a versatile building block in organic chemistry for constructing complex molecules via coupling reactions, cyclizations, or further functionalization.
• Bioconjugation & Probe Development: The carboxylic acid group allows for conjugation to other molecules, making it useful for creating fluorescent probes or biochemical tools.

Basic Information

Product Name	2-Thiophen-2-Yl-1H-Benzoimidazole-5-Carboxylic Acid
CAS No.	174422-11-8
Molecular Formula	C12H8N2O2S
Molecular Weight	244.27 g/mol
Synonyms	2-(Thiophen-2-yl)-1H-benzo[d]imidazole-5-carboxylic acid; 2-(2-Thienyl)-1H-benzimidazole-5-carboxylic acid; 1H-Benzimidazole-5-carboxylic acid, 2-(2-thienyl)-; 174422-11-8; 2-(Thiophen-2-yl)-1H-benzoimidazole-5-carboxylic acid; 2-(2-Thienyl)-5-carboxybenzimidazole; 2-Thien-2-yl-1H-benzoimidazole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Thiophen-2-Yl-1H-Benzoimidazole-5-Carboxylic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support applications in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.