Description

4-Bromo-2-Fluorothiophenol is a versatile organosulfur building block characterized by its reactive thiol and halogenated aromatic structure. This compound is essential for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences and material science sectors for constructing novel thioether linkages and heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated and sulfur-based pharmacophores.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the fluorine and bromine substituents enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the research of novel polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Research: A valuable reagent for academic and industrial research in organic synthesis and methodology development.

Basic Information

Product Name	4-Bromo-2-Fluorothiophenol
CAS No.	174414-93-8
Molecular Formula	C6H4BrFS
Molecular Weight	207.06 g/mol
Synonyms	2-Fluoro-4-bromobenzenethiol; 4-Bromo-2-fluorobenzenethiol; 2-Fluoro-4-bromothiophenol; (4-Bromo-2-fluorophenyl)thiol; Benzenethiol, 4-bromo-2-fluoro-; 174414-93-8; 4-Bromo-2-fluoro-thiophenol
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorothiophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen) to prevent oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.