Description

Ethyl 2-Amino-4-Methyl-5-(4-Nitrophenyl)Thiophene-3-Carboxylate is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile molecular scaffold, which is engineered for the efficient construction of complex pharmacophores and functional materials. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Used in the research and development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Dye & Pigment Synthesis: Acts as an intermediate for creating specialized dyes and pigments, leveraging the nitrophenyl group for color and property tuning.
• Academic & Contract Research: A valuable reagent for methodological studies in heterocyclic chemistry, cross-coupling reactions, and scaffold diversification in university and CRO laboratories.
• Custom Synthesis & Scale-Up: An ideal starting point for custom synthesis projects, offering a defined pathway for gram to kilogram-scale production of target molecules.

Basic Information

Product Name	Ethyl 2-Amino-4-Methyl-5-(4-Nitrophenyl)Thiophene-3-Carboxylate
CAS No.	174072-89-0
Molecular Formula	C15H16N2O4S
Molecular Weight	320.36 g/mol
Synonyms	Ethyl 2-Amino-4-methyl-5-(p-nitrophenyl)thiophene-3-carboxylate; 2-Amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylic acid ethyl ester; 5-(4-Nitrophenyl)-4-methyl-2-aminothiophene-3-carboxylic acid ethyl ester; 174072-89-0; Thiophene-3-carboxylic acid, 2-amino-4-methyl-5-(4-nitrophenyl)-, ethyl ester; p-Nitrophenyl thiophene carboxylate derivative
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-4-Methyl-5-(4-Nitrophenyl)Thiophene-3-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive compound from degradation and to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.