Description

(R)-1-Aza-2-Bora-2-((Trimethylsilyl)Methyl)-3-Oxa-4,4-Diphenylbicyclo<3.3.0>Octane is a sophisticated organoboron reagent featuring a unique bicyclic structure with a chiral center. This compound is valued for its role as a highly selective catalyst or ligand in advanced organic synthesis, particularly in asymmetric transformations. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers developing novel active ingredients and complex molecular architectures.

Application

• Asymmetric Catalysis: As a chiral ligand or catalyst precursor for enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediates: Synthesis of chiral building blocks for active pharmaceutical ingredients (APIs) and drug candidates.
• Organometallic Chemistry: A key reagent in the study and development of new boron-containing catalysts and materials.
• Academic & Industrial Research: Tool for methodological development in synthetic organic chemistry laboratories.
• Material Science: Potential precursor for boron-doped or boron-based advanced materials.

Basic Information

Product Name	(R)-1-Aza-2-Bora-2-((Trimethylsilyl)Methyl)-3-Oxa-4,4-Diphenylbicyclo<3.3.0>Octane
CAS No.	174004-13-8
Molecular Formula	C22H30BNOSi
Molecular Weight	363.38 g/mol
Synonyms	(R)-1-Aza-2-bora-2-((trimethylsilyl)methyl)-3-oxa-4,4-diphenylbicyclo[3.3.0]octane; (R)-1-Aza-2-bora-2-(trimethylsilylmethyl)-3-oxa-4,4-diphenylbicyclo[3.3.0]octane; (R)-1-Aza-2-bora-2-(trimethylsilylmethyl)-3-oxa-4,4-diphenylbicyclo[3.3.0]octane; (R)-1-Aza-2-bora-2-(trimethylsilylmethyl)-3-oxa-4,4-diphenylbicyclo[3.3.0]octane; (R)-1-Aza-2-bora-2-(trimethylsilylmethyl)-3-oxa-4,4-diphenylbicyclo[3.3.0]octane; (R)-1-Aza-2-bora-2-(trimethylsilylmethyl)-3-oxa-4,4-diphenylbicyclo[3.3.0]octane; (R)-1-Aza-2-bora-2-(trimethylsilylmethyl)-3-oxa-4,4-diphenylbicyclo[3.3.0]octane; (R)-1-Aza-2-bora-2-(trimethylsilylmethyl)-3-oxa-4,4-diphenylbicyclo[3.3.0]octane
EINECS	Contact for details

Quality Control

Our (R)-1-Aza-2-Bora-2-((Trimethylsilyl)Methyl)-3-Oxa-4,4-Diphenylbicyclo<3.3.0>Octane is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.