Description

5,7-Difluoro-Indan-1-Ylamine is a high-purity fluorinated indane derivative serving as a critical chiral building block in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine atoms and the reactive primary amine group, enabling precise modifications to molecular scaffolds for enhanced bioactivity and physicochemical properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in constructing advanced fluorinated molecules for next-generation herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated organic compounds for electronic materials and specialty polymers.
• Chemical Biology Probes: Utilized to develop fluorinated molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	5,7-Difluoro-Indan-1-Ylamine
CAS No.	173998-72-6
Molecular Formula	C9H9F2N
Molecular Weight	169.17 g/mol
Synonyms	1-Amino-5,7-difluoroindane; 5,7-Difluoro-1-indanamine; (5,7-Difluoro-2,3-dihydro-1H-inden-1-yl)amine; 5,7-Difluoroindan-1-amine; 1-Indanamine, 5,7-difluoro-; 173998-72-6; 5,7-Difluoro-1-indanylamine
EINECS	Contact for details

Quality Control

Every batch of 5,7-Difluoro-Indan-1-Ylamine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and development. Certificates of Analysis (COA) detailing purity by HPLC, chiral purity, and impurity profiles are provided with each shipment. We support custom synthesis to meet specific pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.