Description

tert-Butyl 4-(3-Methyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex molecules, offering a versatile piperidine scaffold with a benzimidazolone moiety. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The benzimidazolone-piperidine structure is relevant for designing inhibitors targeting various enzymatic pathways.
• Chemical Biology: Employed in the development of molecular probes and tool compounds for biological target validation.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.

Basic Information

Product Name	tert-Butyl 4-(3-Methyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Piperidine-1-Carboxylate
CAS No.	173843-48-6
Molecular Formula	C18H25N3O3
Molecular Weight	331.41 g/mol
Synonyms	1-Boc-4-(3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine; 1-(1-Boc-4-piperidinyl)-3-methyl-1,3-dihydro-2H-benzimidazol-2-one; tert-Butyl 4-(3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxylate; 1-(1-(tert-Butoxycarbonyl)-4-piperidinyl)-3-methyl-1,3-dihydro-2H-benzimidazol-2-one; 4-(3-Methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester; BOC-protected benzimidazolone piperidine; 173843-48-6
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-(3-Methyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-1-Yl)Piperidine-1-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.