Description

Bicyclo[2.2.2]Octane-2-Methanol, 1-Ethoxy-5-Hydroxy-3-Methyl-, (1Alpha,2Alpha,3Ba,4Ba,5Alpha)- (9Ci) is a complex, multi-functional bicyclic organic compound that serves as a valuable chiral building block and intermediate in advanced chemical synthesis. Its unique, rigid bicyclo[2.2.2]octane scaffold, combined with strategically positioned ethoxy, hydroxy, and methyl substituents, makes it a critical precursor for developing novel pharmaceuticals, agrochemicals, and specialty materials. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, fine chemical, and advanced material sectors who require structurally defined, stereochemically pure components for complex molecule assembly.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used as a building block for creating novel, high-performance pesticides and herbicides with specific stereochemical requirements for enhanced biological activity.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated chiral ligands and organocatalysts for asymmetric synthesis applications.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of polymers with specific rigid, three-dimensional architectures for advanced material properties.
• Academic and Industrial R&D: A valuable tool compound for methodological studies in organic synthesis, stereochemistry, and total synthesis of natural products.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance ingredients, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-2-Methanol, 1-Ethoxy-5-Hydroxy-3-Methyl-, (1Alpha,2Alpha,3Ba,4Ba,5Alpha)- (9Ci)
CAS No.	173672-42-9
Molecular Formula	C12H22O3
Molecular Weight	214.30 g/mol
Synonyms	(1α,2α,3β,4β,5α)-1-Ethoxy-5-hydroxy-3-methylbicyclo[2.2.2]octane-2-methanol; 1-Ethoxy-5-hydroxy-3-methylbicyclo[2.2.2]octane-2-methanol (stereoisomer); Bicyclo[2.2.2]octane-2-methanol, 1-ethoxy-5-hydroxy-3-methyl-, (1α,2α,3β,4β,5α)-; Bicyclo[2.2.2]octane-2-methanol, 1-ethoxy-5-hydroxy-3-methyl-, (1.alpha.,2.alpha.,3.beta.,4.beta.,5.alpha.)-; (1.alpha.,2.alpha.,3.beta.,4.beta.,5.alpha.)-1-Ethoxy-5-hydroxy-3-methylbicyclo[2.2.2]octane-2-methanol; CAS 173672-42-9
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octane-2-Methanol, 1-Ethoxy-5-Hydroxy-3-Methyl-, (1Alpha,2Alpha,3Ba,4Ba,5Alpha)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity, precise stereochemical integrity, and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles are provided and available upon request. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed when not in use to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.