Description

1H-Pyrrolo[1,2-C]Imidazol-1-One,2-Ethylhexahydro-6-Hydroxy-,(6R-Trans)-(9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. Its value lies in its complex, fused-ring structure which serves as a critical chiral building block or intermediate for the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and development teams in the pharmaceutical and fine chemical industries seeking to create new therapeutic agents with specific stereochemical properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) or anti-infective agents.
• Advanced Organic Synthesis: Serves as a sophisticated building block for constructing complex, polycyclic molecular architectures in medicinal chemistry.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development of new stereoselective catalytic processes.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential APIs, requiring high chemical and optical purity.
• Chemical Reference Standard: Provides a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	1H-Pyrrolo[1,2-C]Imidazol-1-One,2-Ethylhexahydro-6-Hydroxy-,(6R-Trans)-(9Ci)
CAS No.	173658-17-8
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	(6R-trans)-2-Ethylhexahydro-6-hydroxy-1H-pyrrolo[1,2-c]imidazol-1-one; 2-Ethylhexahydro-6-hydroxy-1H-pyrrolo[1,2-c]imidazol-1-one, (6R-trans)-; Hexahydro-6-hydroxy-2-ethyl-1H-pyrrolo[1,2-c]imidazol-1-one, (6R-trans)-; 173658-17-8; (6R)-2-Ethyl-6-hydroxyhexahydro-1H-pyrrolo[1,2-c]imidazol-1-one
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up work. Quality is verified through comprehensive analytical techniques including HPLC, chiral HPLC, 1H/13C NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) documenting all relevant specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.