Description

Dichloroacetic Acid-1-13C is a stable isotope-labeled derivative of dichloroacetic acid, where the carbon-1 position is enriched with the 13C isotope. This precise labeling is critical for applications requiring high specificity in analytical and metabolic studies. It serves as an essential tool for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors who require isotopically labeled compounds for tracer studies, quantitative analysis, and advanced research methodologies.

Application

• As an internal standard for the precise quantification of dichloroacetic acid and related metabolites in biological and environmental samples via Gas Chromatography-Mass Spectrometry (GC-MS) or Liquid Chromatography-Mass Spectrometry (LC-MS).
• A key precursor or labeled intermediate in the synthesis of more complex 13C-labeled pharmaceutical compounds for drug metabolism and pharmacokinetics (DMPK) studies.
• Use in metabolic pathway tracing and flux analysis to investigate biochemical mechanisms in cancer research and cellular metabolism.
• Employed in environmental science for tracing the degradation pathways of chlorinated acetic acids.
• Utilized as a reagent in nuclear magnetic resonance (NMR) spectroscopy as a chemical shift reference or for mechanistic studies.
• Application in the development and calibration of clinical diagnostic assays for metabolic disorders.

Basic Information

Product Name	Dichloroacetic Acid-1-13C
CAS No.	173470-70-7
Molecular Formula	C13CHCl2COOH
Molecular Weight	129.93 g/mol (for 13C1)
Synonyms	Dichloroacetic-1-13C Acid; [1-13C]Dichloroacetic Acid; DCA-1-13C; 2,2-Dichloroacetic-1-13C Acid; (13C)Dichloroacetic Acid; Isotopically Labeled Dichloroacetic Acid; Dichloroethanoic-1-13C Acid
EINECS	Contact for details

Quality Control

Our Dichloroacetic Acid-1-13C is produced under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (atom % 13C), chemical purity, and identity confirmation. We adhere to rigorous in-house quality standards to ensure batch-to-batch consistency and reliability for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 8°C to maximize stability. Handle and store this strong acid/organic solvent with appropriate precautions in a dedicated chemical storage area.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Enrichment (Atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.