Description

[1-(1'(R)-α-Methylbenzyl)-Aziridine-2(S)-Yl]-Methanol is a high-purity, chiral aziridine derivative of significant importance in asymmetric synthesis. This compound serves as a versatile and valuable chiral building block for the preparation of complex pharmaceutical intermediates and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of enantiomerically pure active ingredients.

Application

• As a key chiral synthon in the asymmetric synthesis of pharmaceutical candidates.
• For the preparation of ligands and catalysts used in enantioselective transformations.
• In the research and development of protease inhibitors and other biologically active molecules.
• As a building block for advanced intermediates in agrochemical and fine chemical production.
• For methodology development in organic and medicinal chemistry research.
• In the synthesis of custom amino alcohol derivatives with specific stereochemistry.

Basic Information

Product Name	[1-(1'(R)-α-Methylbenzyl)-Aziridine-2(S)-Yl]-Methanol
CAS No.	173143-73-2
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	(2S)-2-(Hydroxymethyl)-1-[(1R)-1-phenylethyl]aziridine; (2S)-1-[(1R)-1-Phenylethyl]aziridine-2-methanol; (1R,2S)-1-(1-Phenylethyl)-2-(hydroxymethyl)aziridine; (R)-1-Phenylethyl-(S)-2-hydroxymethylaziridine; Chiral Aziridine Methanol Derivative; (S)-2-(Hydroxymethyl)-1-((R)-1-phenylethyl)aziridine; Aziridine-2-methanol, 1-[(1R)-1-phenylethyl]-, (2S)-
EINECS	Contact for details

Quality Control

Our [1-(1'(R)-α-Methylbenzyl)-Aziridine-2(S)-Yl]-Methanol is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles, verified by techniques including HPLC, GC, and chiral analysis. We support cGMP and ISO compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This material is hygroscopic and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.