Description

Cyclohexanethiol,5-Methyl-2-(1-Methylethyl)-,(1S,2R,5S)-(9Ci) is a high-purity, chiral thiol derivative of menthol, offering a unique combination of a robust mercaptan functional group with a defined stereochemistry. This compound matters for advanced chemical synthesis where precise molecular architecture and sulfur-based reactivity are critical. It is primarily needed by R&D chemists and process developers in the pharmaceutical and fine chemical industries for applications such as chiral ligand synthesis, asymmetric catalysis, and as a building block for complex bioactive molecules. CAS No. 173006-99-0.

Application

• Chiral Ligand & Catalyst Synthesis: Serves as a key precursor for developing novel sulfur-containing ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Pharmaceutical Intermediates: Acts as a sophisticated building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a stereodefined thiol moiety.
• Flavor & Fragrance Chemistry: Utilized in the research and development of high-value aroma chemicals, leveraging its menthol-related structure for unique organoleptic properties.
• Polymer Modification: Employed as a functional monomer or chain-transfer agent to introduce specific thiol groups into polymers, altering their physical or adhesive properties.
• Chemical Research & Development: A valuable tool compound for exploring new thiol-ene click chemistry reactions and other sulfur-based organic methodologies.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents where the specific stereochemistry can influence biological activity.

Basic Information

Product Name	Cyclohexanethiol,5-Methyl-2-(1-Methylethyl)-,(1S,2R,5S)-(9Ci)
CAS No.	173006-99-0
Molecular Formula	C10H20S
Molecular Weight	172.33 g/mol
Synonyms	(1S,2R,5S)-5-Methyl-2-(1-methylethyl)cyclohexanethiol; (-)-Menthyl mercaptan; (1S,2R,5S)-2-Isopropyl-5-methylcyclohexanethiol; L-Menthyl mercaptan; (-)-Menthanethiol; (1S,2R,5S)-Menthyl mercaptan; Thio-(-)-menthol
EINECS	Contact for details

Quality Control

Our production of Cyclohexanethiol,5-Methyl-2-(1-Methylethyl)-,(1S,2R,5S)-(9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C to maximize stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Chiral Purity (e.e.)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.