Description

Boc-2-Aminobicyclo[2.2.1]Heptane-2-Carboxylicacid (Mixture Of Isomers) is a protected amino acid derivative featuring a rigid, bicyclic norbornane scaffold. This compound is a crucial chiral building block for medicinal chemistry, enabling the synthesis of conformationally constrained peptides and peptidomimetics. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams to develop novel therapeutic agents, particularly in areas requiring enhanced metabolic stability and receptor selectivity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of protease inhibitors, receptor antagonists, and other bioactive molecules.
• Peptidomimetic Design: Used to introduce conformational rigidity into peptide backbones, improving stability against enzymatic degradation.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in the synthesis of complex, enantiomerically pure compounds.
• Chemical Biology Probes: Incorporated into molecular probes to study protein-protein interactions and enzyme mechanisms.
• Agrochemical Research: Potential building block for novel active ingredients with specific stereochemical requirements.
• Academic & Contract Research: Employed in research institutions and CROs for exploratory chemistry and library synthesis.

Basic Information

Product Name	Boc-2-Aminobicyclo[2.2.1]Heptane-2-Carboxylicacid (Mixture Of Isomers)
CAS No.	172927-01-4
Molecular Formula	C₁₄H₂₃NO₄
Molecular Weight	269.34 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]bicyclo[2.2.1]heptane-2-carboxylic acid; N-Boc-2-aminonorbornane-2-carboxylic acid; tert-Butyl (2-carboxybicyclo[2.2.1]heptan-2-yl)carbamate; BOC-Amino(2-norbornane)carboxylic Acid; N-(tert-Butoxycarbonyl)-2-aminobicyclo[2.2.1]heptane-2-carboxylic acid; Boc-2-Abn-OH (mixture of isomers); 172927-01-4
EINECS	Contact for details

Quality Control

Our Boc-2-Aminobicyclo[2.2.1]Heptane-2-Carboxylicacid (Mixture Of Isomers) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and isomer ratio.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomer Ratio (by HPLC)	Specified on COA
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.