Description

Boronic Acid, B-(4-Bromo-3,5-Dimethyl-2-Thienyl)- is a high-purity, heterocyclic boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in materials science for creating advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing thiophene and biaryl motifs for oncology, CNS, and anti-infective applications.
• Agrochemical Synthesis: Used in constructing active molecules for crop protection agents, including fungicides and herbicides, leveraging its bromo and thienyl functional groups.
• Material Science Research: Building block for creating conjugated polymers and organic semiconductors used in OLEDs, OFETs, and photovoltaic cells.
• Chemical Biology & Probe Development: Utilized in synthesizing molecular probes and sensors that leverage boronic acid-diol interactions for detecting sugars or other biomolecules.
• Catalyst & Ligand Preparation: Serves as a precursor for synthesizing specialized ligands and catalysts used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Boronic Acid, B-(4-Bromo-3,5-Dimethyl-2-Thienyl)-
CAS No.	172872-73-0
Molecular Formula	C8H10BBrO2S
Molecular Weight	261.94 g/mol
Synonyms	(4-Bromo-3,5-dimethylthiophen-2-yl)boronic acid; 4-Bromo-3,5-dimethyl-2-thienylboronic acid; 2-Thienylboronic acid, 4-bromo-3,5-dimethyl-; B-(4-Bromo-3,5-dimethyl-2-thienyl)boronic acid; 4-Bromo-3,5-dimethylthiophene-2-boronic acid; (4-Bromo-3,5-dimethyl-2-thienyl)boronic Acid; Boronic acid, B-(4-bromo-3,5-dimethyl-2-thienyl)-
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-(4-Bromo-3,5-Dimethyl-2-Thienyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.