Description

Ethyl 6,6-Dimethyl-3-(Methylsulfonyl)-4-Oxo-4,5,6,7-Tetrahydrobenzo[C]Thiophene-1-Carboxylate is a high-purity, synthetically valuable heterocyclic building block designed for advanced chemical synthesis. This compound matters as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a unique fused-ring scaffold with multiple functional handles. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Serves as a core scaffold for developing new generations of herbicides, fungicides, or insecticides with improved efficacy and environmental profiles.
• Material Science Chemistry: Used in the research and development of advanced organic electronic materials or specialty polymers due to its electron-deficient thiophene core.
• Organic Synthesis Building Block: Employed in medicinal and combinatorial chemistry for constructing complex, polyfunctional heterocyclic libraries for high-throughput screening.
• Chemical Reference Standard: Supplied as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	Ethyl 6,6-Dimethyl-3-(Methylsulfonyl)-4-Oxo-4,5,6,7-Tetrahydrobenzo[C]Thiophene-1-Carboxylate
CAS No.	172516-46-0
Molecular Formula	C15H18O5S2
Molecular Weight	342.43 g/mol
Synonyms	Ethyl 6,6-dimethyl-3-(methylsulfonyl)-4-oxo-4,5,6,7-tetrahydro-1-benzothiophene-1-carboxylate; 1-Benzothiophene-1-carboxylic acid, 4,5,6,7-tetrahydro-6,6-dimethyl-3-(methylsulfonyl)-4-oxo-, ethyl ester; 172516-46-0; Ethyl 3-(Methylsulfonyl)-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydrobenzo[c]thiophene-1-carboxylate; 4,5,6,7-Tetrahydro-6,6-dimethyl-3-(methylsulfonyl)-4-oxo-1-benzothiophene-1-carboxylic Acid Ethyl Ester.
EINECS	Contact for details

Quality Control

Our Ethyl 6,6-Dimethyl-3-(Methylsulfonyl)-4-Oxo-4,5,6,7-Tetrahydrobenzo[C]Thiophene-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.