Description

Bicyclo[3.1.0]Hexan-3-Ol, 1-Ethynyl-2-Methylene-, [1S-(1Alpha,3Beta,5Alpha)]- (9Ci) is a high-value, stereochemically defined bicyclic organic compound featuring both alkyne and alkene functional groups. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile chiral building block for complex organic synthesis. It is primarily sought after by R&D and process chemistry teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Synthesis: Used as a building block for creating novel pesticides and herbicides with specific stereochemical activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of novel polymers and functional organic materials due to its reactive alkyne and alkene groups.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including cycloaddition reactions and stereoselective synthesis.
• Fine Chemical Production: Used in the multi-step synthesis of other high-value, complex fine chemicals and specialty compounds.

Basic Information

Item	Details
Product Name	Bicyclo[3.1.0]Hexan-3-Ol, 1-Ethynyl-2-Methylene-, [1S-(1Alpha,3Beta,5Alpha)]- (9Ci)
CAS No.	172491-36-0
Molecular Formula	C9H10O
Molecular Weight	134.18 g/mol
Synonyms	(1S,3R,5S)-1-Ethynyl-2-methylidenebicyclo[3.1.0]hexan-3-ol; (1S,3R,5S)-1-Ethynyl-2-methylenebicyclo[3.1.0]hexan-3-ol; 1-Ethynyl-2-methylenebicyclo[3.1.0]hexan-3-ol, (1S,3R,5S)-; Bicyclo[3.1.0]hexan-3-ol, 1-ethynyl-2-methylene-, (1S,3R,5S)-; (1S,3R,5S)-1-Ethynyl-2-methylidenebicyclo[3.1.0]hexan-3-ol (9CI); 172491-36-0; 1-Ethynyl-2-methylenebicyclo[3.1.0]hexan-3-ol (stereoisomer)
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[3.1.0]Hexan-3-Ol, 1-Ethynyl-2-Methylene-, [1S-(1Alpha,3Beta,5Alpha)]- (9Ci) is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing chiral purity, assay, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the container in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated). Allow the container to reach room temperature before opening to prevent moisture condensation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.