Description

(3Z)-3-[(Benzylamino)Methylidene]-1-(2,6-Dichlorophenyl)Indol-2-One is a high-purity, non-natural indole derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical synthetic intermediate for constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the discovery of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead molecules.
• Chemical Biology Probes: Serves as a precursor for developing labeled compounds or probes to study biological pathways and protein interactions.
• Organic Synthesis: A valuable reagent for constructing complex heterocyclic systems and indole-fused structures in academic and industrial R&D settings.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.

Basic Information

Product Name	(3Z)-3-[(Benzylamino)Methylidene]-1-(2,6-Dichlorophenyl)Indol-2-One
CAS No.	172371-92-5
Molecular Formula	C22H16Cl2N2O
Molecular Weight	395.28 g/mol
Synonyms	1-(2,6-Dichlorophenyl)-3-[(phenylmethylamino)methylene]-2-indolinone; (Z)-3-((Benzylamino)methylene)-1-(2,6-dichlorophenyl)indolin-2-one; 3-[(Benzylamino)methylidene]-1-(2,6-dichlorophenyl)-1,3-dihydro-2H-indol-2-one; 1-(2,6-Dichlorophenyl)-3-[(phenylmethylamino)methylidene]-2-indolinone; 172371-92-5; (3Z)-3-[(Benzylamino)Methylidene]-1-(2,6-Dichlorophenyl)-2-Indolinone
EINECS	Contact for details

Quality Control

Our (3Z)-3-[(Benzylamino)Methylidene]-1-(2,6-Dichlorophenyl)Indol-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.