Description

cis-3-Benzyloxymethylcyclobutanol CAS NO 172324-68-4 is a high-purity, functionalized cyclobutane derivative characterized by its cis-configuration and benzyl-protected alcohol moiety. This compound serves as a versatile and valuable chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the preparation of novel pesticides and herbicides, leveraging its rigid cyclobutane core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with unique structural properties.
• Academic & Industrial R&D: A valuable tool for methodological studies and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	cis-3-Benzyloxymethylcyclobutanol
CAS No.	172324-68-4
Molecular Formula	C12H16O2
Molecular Weight	192.26 g/mol
Synonyms	cis-3-(Benzyloxymethyl)cyclobutanol; (1s,3s)-3-(Benzyloxymethyl)cyclobutanol; 3-[(Phenylmethoxy)methyl]cyclobutanol (cis-); Cyclobutanol, 3-[(phenylmethoxy)methyl]-, cis-; BOC Sciences Brand Name: BBL-B-00332; (1R,3R)-3-(Benzyloxymethyl)cyclobutanol (enantiomer); 172324-68-4
EINECS	Contact for details

Quality Control

Our cis-3-Benzyloxymethylcyclobutanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.