Description

1H-Pyrazole, 1-Ethyl-4-Iodo- is a halogenated pyrazole derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in its functionalized structure, which enables the construction of complex heterocyclic systems and facilitates key coupling reactions. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the pyrazole core's bioactivity.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings to form carbon-carbon bonds.
• Ligand Synthesis: Utilized for preparing novel nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.

Basic Information

Product Name	1H-Pyrazole, 1-Ethyl-4-Iodo-
CAS No.	172282-34-7
Molecular Formula	C5H7IN2
Molecular Weight	222.03 g/mol
Synonyms	1-Ethyl-4-iodo-1H-pyrazole; 4-Iodo-1-ethylpyrazole; 1-Ethyl-4-iodopyrazole; 1-Ethyl-4-iodo-1H-pyrazole; 172282-34-7; Ethyl iodopyrazole; Iodoethylpyrazole
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole, 1-Ethyl-4-Iodo- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.