Description

2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethanethioamide is a specialized organic compound featuring a phthalimide core linked to a thioamide functional group, making it a valuable synthetic intermediate. This compound matters for its role in constructing complex molecules, particularly in the development of pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that incorporate the phthalimide pharmacophore.
• Organic Synthesis Reagent: Serves as a versatile precursor for the introduction of thioamide and imide functionalities into more complex molecular architectures.
• Material Science: Potential monomer or additive in the research of polymers with specific thermal or optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme inhibition or protein-ligand interactions.

Basic Information

Product Name	2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethanethioamide
CAS No.	172261-05-1
Molecular Formula	C10H8N2O2S
Molecular Weight	220.25 g/mol
Synonyms	2-(1,3-Dioxoisoindolin-2-yl)ethanethioamide; 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethanethioamide; N-(Carbamothioylmethyl)phthalimide; 2-(1,3-Dioxoisoindolin-2-yl)acetothioamide; 2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)ethanethioamide; 2-(1,3-Dioxo-1,3-dihydro-2H-benzo[de]isoquinolin-2-yl)ethanethioamide (related structure); Phthalimidothioacetamide
EINECS	Contact for details

Quality Control

Our 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethanethioamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.