Description

tert-Butyl 2-(2-Ethoxy-1,1-Dimethyl-2-Oxoethyl)-1H-Indole-1-Carboxylate CAS NO 172226-79-8 is a high-purity, protected indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, enabling precise chemical transformations. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for organic electronic materials and functional dyes.
• Academic & Contract Research: A valuable reagent for methodological development and complex molecule synthesis in university and CRO laboratories.
• Peptidomimetics: Employed in the design and synthesis of peptide analogs and protease inhibitors.
• Chemical Biology Probes: Utilized to create labeled compounds for studying biological pathways and target engagement.

Basic Information

Product Name	tert-Butyl 2-(2-Ethoxy-1,1-Dimethyl-2-Oxoethyl)-1H-Indole-1-Carboxylate
CAS No.	172226-79-8
Molecular Formula	C19H25NO4
Molecular Weight	331.41 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 2-[2-ethoxy-1,1-dimethyl-2-oxoethyl]-, 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-2-(2-ethoxy-1,1-dimethyl-2-oxoethyl)indole; Boc-2-(2-Ethoxy-1,1-dimethyl-2-oxoethyl)indole; tert-Butyl 2-(α-ethoxycarbonylisopropyl)-1H-indole-1-carboxylate; 2-(2-Ethoxy-1,1-dimethyl-2-oxoethyl)-1H-indole-1-carboxylic acid tert-butyl ester; N-Boc-2-(2-ethoxy-1,1-dimethyl-2-oxoethyl)indole; 172226-79-8; tert-Butyl 2-(2-ethoxy-1,1-dimethyl-2-oxoethyl)indole-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(2-Ethoxy-1,1-Dimethyl-2-Oxoethyl)-1H-Indole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.