Description

7-(Trifluoromethyl)-1H-Indole is a high-value fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethyl group, which is essential for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF₃ group enhances lipophilicity and metabolic stability.
• Material Science: Building block for functional materials, including organic light-emitting diodes (OLEDs) and specialty polymers.
• Chemical Research: Versatile reagent in academic and industrial R&D for exploring new fluorination chemistry and heterocyclic compound libraries.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	7-(Trifluoromethyl)-1H-Indole
CAS No.	172217-02-6
Molecular Formula	C₉H₆F₃N
Molecular Weight	185.15 g/mol
Synonyms	7-(Trifluoromethyl)indole; 1H-Indole, 7-(trifluoromethyl)-; 7-Trifluoromethylindole; 7-CF3-Indole; 7-(Trifluoromethyl)-1H-indole; 172217-02-6; 7-(Trifluoromethyl)indole; 7-Trifluoromethyl-1H-indole
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.