Description

7-(Trifluoromethyl)-1H-Indole-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block characterized by its indole core and trifluoromethyl substituent. This compound matters for its critical role in modern medicinal chemistry and agrochemical research, where it serves as a privileged scaffold for developing novel active ingredients. Pharmaceutical, agrochemical, and advanced material R&D teams need this intermediate to synthesize new drug candidates, crop protection agents, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents, including kinase inhibitors, anti-inflammatory drugs, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the indole moiety and the metabolic stability imparted by the trifluoromethyl group.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag in biochemical research to study protein interactions and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for the custom synthesis of complex molecules for client-specific projects.
• Academic Research: Used in university and institutional laboratories for methodological development and exploration of new chemical reactions involving fluorinated indoles.

Basic Information

Product Name	7-(Trifluoromethyl)-1H-Indole-2-Carboxylic Acid
CAS No.	172216-98-7
Molecular Formula	C10H6F3NO2
Molecular Weight	229.16 g/mol
Synonyms	7-(Trifluoromethyl)-1H-indole-2-carboxylic acid; 2-Carboxy-7-(trifluoromethyl)indole; 7-Trifluoromethylindole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 7-(trifluoromethyl)-; 172216-98-7; 7-(Trifluoromethyl)indole-2-carboxylic acid; 2-Indolecarboxylic acid, 7-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.