Description

8A(1H)-Indolizinecarboxylicacid,6-Aminohexahydro-5-Oxo-,(6S-Trans)-(9Ci) is a high-purity, stereochemically defined indolizine derivative, a crucial advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of complex, biologically active molecules, enabling precise molecular construction. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those focused on novel drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for the design and construction of new chemical entities with targeted biological activity.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes from lab to pilot plant.
• Bioconjugation & Probe Synthesis: Potential use in creating labeled compounds or molecular probes for biochemical and diagnostic research.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce complex molecular frameworks with high enantiomeric purity.

Basic Information

Product Name	8A(1H)-Indolizinecarboxylicacid,6-Aminohexahydro-5-Oxo-,(6S-Trans)-(9Ci)
CAS No.	172140-60-2
Molecular Formula	C9H14N2O3
Molecular Weight	198.22 g/mol
Synonyms	(6S)-6-Amino-5-oxohexahydro-8a(1H)-indolizinecarboxylic acid; (6S-trans)-6-Amino-5-oxohexahydro-8a(1H)-indolizine-8a-carboxylic acid; 8a(1H)-Indolizinecarboxylic acid, 6-aminohexahydro-5-oxo-, (6S-trans)-; 172140-60-2; (6S)-6-Amino-5-oxoperhydroindolizine-8a-carboxylic acid; (6S)-6-Amino-5-oxo-octahydroindolizine-8a-carboxylic acid; A key indolizine carboxylic acid derivative.
EINECS	Contact for details

Quality Control

Our high-value chemical intermediates are produced under strict quality management systems. Each batch of 8A(1H)-Indolizinecarboxylicacid,6-Aminohexahydro-5-Oxo-,(6S-Trans)-(9Ci) undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under inert atmosphere at 2-8°C to maintain optimal stability. The container should be kept in a well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.