Description

3-Chloro-5-Methoxybenzo[B]Thiophene-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile scaffold for molecular diversification. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Used in the research and development of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Synthesis: Functions as a versatile scaffold for Suzuki-Miyaura, Buchwald-Hartwig, and other cross-coupling reactions to create complex molecular architectures.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory chemistry and method development.

Basic Information

Product Name	3-Chloro-5-Methoxybenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	172088-61-8
Molecular Formula	C10H7ClO3S
Molecular Weight	242.68 g/mol
Synonyms	3-Chloro-5-methoxybenzo[b]thiophene-2-carboxylic acid; 3-Chloro-5-methoxy-1-benzothiophene-2-carboxylic acid; 2-Benzothiophenecarboxylic acid, 3-chloro-5-methoxy-; 172088-61-8; 3-Chloro-5-methoxybenzo[b]thiophene-2-carboxylate; 3-Chloro-5-methoxy-2-benzothiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Methoxybenzo[B]Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.