Description

3-Amino-3-(2-Bromophenyl)Propan-1-Ol is a specialized chiral amino alcohol building block featuring both a bromoaryl group and a primary alcohol functionality. This compound matters for its role as a critical intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting central nervous system (CNS) disorders. Pharmaceutical R&D and fine chemical synthesis companies need this high-purity intermediate to develop new active pharmaceutical ingredients (APIs) and chiral ligands for asymmetric catalysis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential CNS-active drugs, antidepressants, and neuroleptic agents.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis.
• Agrochemical Research: Utilized in the development of novel, bioactive compounds for crop protection.
• Academic & R&D Laboratories: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Synthesis: Used to construct more complex molecular architectures requiring a brominated, amino-substituted side chain.

Basic Information

Product Name	3-Amino-3-(2-Bromophenyl)Propan-1-Ol
CAS No.	171911-83-4
Molecular Formula	C9H12BrNO
Molecular Weight	230.10 g/mol
Synonyms	3-Amino-3-(2-bromophenyl)-1-propanol; 2-Bromo-β-aminohydrocinnamyl alcohol; 1-Propanol, 3-amino-3-(2-bromophenyl)-; (RS)-3-Amino-3-(2-bromophenyl)propan-1-ol; (±)-3-Amino-3-(2-bromophenyl)propan-1-ol; 3-Amino-3-(o-bromophenyl)propan-1-ol; β-Amino-β-(2-bromophenyl)propanol
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(2-Bromophenyl)Propan-1-Ol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.