Description

4-Bromo-5-Nitro-Isoquinoline-1-Carbaldehyde is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring both bromo and nitro substituents on the isoquinoline core, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in oncology and CNS research, leveraging its reactive aldehyde and halogenated nitroaromatic functionalities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the isoquinoline scaffold can impart specific biological activity.
• Material Science Precursor: Serves as a building block for creating organic ligands in catalysis, as well as for synthesizing advanced organic electronic materials and dyes.
• Chemical Biology Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new heterocyclic chemistry.
• Custom Synthesis: Acts as a starting material for the contract manufacturing of bespoke, high-value specialty chemicals for client-specific applications.

Basic Information

Product Name	4-Bromo-5-Nitro-Isoquinoline-1-Carbaldehyde
CAS No.	171880-56-1
Molecular Formula	C₁₀H₅BrN₂O₃
Molecular Weight	281.06 g/mol
Synonyms	1-Isoquinolinecarboxaldehyde, 4-bromo-5-nitro-; 4-Bromo-5-nitro-1-isoquinolinecarboxaldehyde; 4-Bromo-5-nitroisoquinoline-1-carbaldehyde; 5-Nitro-4-bromo-1-isoquinolinecarboxaldehyde; 4-Bromo-5-nitro-1-formylisoquinoline; 171880-56-1; 4-Br-5-NO₂-IQ-1-CHO
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-5-Nitro-Isoquinoline-1-Carbaldehyde is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.