Description

3-Amino-6-Fluoro-1-Methylindazole is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique indazole core substituted with reactive amino and fluorine groups, enabling precise molecular modifications. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Material Science: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and nucleophilic substitution reactions.
• Academic & Contract Research: Utilized in universities and CROs for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Amino-6-Fluoro-1-Methylindazole
CAS No.	171809-13-5
Molecular Formula	C8H8FN3
Molecular Weight	165.17 g/mol
Synonyms	6-Fluoro-1-methyl-1H-indazol-3-amine; 1-Methyl-6-fluoro-1H-indazol-3-amine; 3-Amino-6-fluoro-1-methyl-1H-indazole; 6-Fluoro-1-methylindazol-3-ylamine; 1-Methyl-6-fluoroindazol-3-amine; 171809-13-5; 3-Amino-6-fluoro-1-methylindazole
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Fluoro-1-Methylindazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.