Description

3-Amino-5-Fluoro-1-Methylindazole is a high-purity, functionalized indazole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which combines a reactive amino group with a fluorine substituent, enabling precise modifications for developing novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorinated indazole core.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers and liquid crystals.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag due to its reactive amine group, useful for studying enzyme interactions and protein labeling.
• Academic & Contract Research: A valuable reagent for synthetic chemistry research in universities and contract research organizations (CROs).

Basic Information

Product Name	3-Amino-5-Fluoro-1-Methylindazole
CAS No.	171809-12-4
Molecular Formula	C8H8FN3
Molecular Weight	165.17 g/mol
Synonyms	5-Fluoro-1-methyl-1H-indazol-3-amine; 1-Methyl-5-fluoro-1H-indazol-3-amine; 3-Amino-5-fluoro-1-methyl-1H-indazole; 5-Fluoro-1-methylindazol-3-ylamine; 1-Methyl-5-fluoroindazol-3-amine; 171809-12-4; 3-Amino-5-fluoro-1-methylindazole
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-5-Fluoro-1-Methylindazole is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.