Description

Milbemycin B, 5-o-Demethyl-28-Deoxy-6,28-Epoxy-25-Ethyl-13-[[(Methoxyimino)Phenylacetyl]Oxy]-, (6R,13R,25R)- (9Ci) is a chemically modified derivative of the milbemycin family of macrolide compounds, known for its potent biological activity. This high-purity intermediate is critical for the research and development of novel pharmaceutical agents, particularly in the fields of parasitology and veterinary medicine. It serves as a key building block for scientists and manufacturers developing next-generation antiparasitic treatments, offering a reliable and well-characterized starting material for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of advanced antiparasitic active pharmaceutical ingredients (APIs).
• Veterinary Drug R&D: Used in research to develop new formulations for the control of internal and external parasites in livestock and companion animals.
• Agrochemical Research: Investigated for potential applications in crop protection due to its mechanism of action against nematodes and arthropods.
• Biochemical Studies: Serves as a reference standard or probe in studies of chloride channel modulation and neurological targets in parasites.
• Process Chemistry: Employed in scaling up and optimizing synthetic routes for milbemycin-derived compounds under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	Milbemycin B, 5-o-Demethyl-28-Deoxy-6,28-Epoxy-25-Ethyl-13-[[(Methoxyimino)Phenylacetyl]Oxy]-, (6R,13R,25R)- (9Ci)
CAS No.	171249-05-1
Molecular Formula	C38H55NO8
Molecular Weight	653.85 g/mol
Synonyms	5-O-Demethyl-28-deoxy-6,28-epoxy-25-ethyl-13-[[(methoxyimino)phenylacetyl]oxy]milbemycin B; (6R,13R,25R)-Milbemycin B derivative; 13-O-[(Methoxyimino)(phenyl)acetyl]milbemycin B; 171249-05-1; Milbemycin B oxime ether; 5-Desmethyl-28-deoxy-6,28-epoxy-25-ethylmilbemycin B 13-(O-methoxyiminophenylacetate)
EINECS	Contact for details

Quality Control

Our Milbemycin B derivative is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC and NMR. We support development and commercial projects with material suitable for research use and can provide material manufactured under GMP-grade conditions upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The compound is light-sensitive (store away from light). For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.