Description

Methyl 3-Amino-Thieno[3,2-B]Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate (API) with the CAS number 171179-86-5. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its unique fused-ring structure that enables the synthesis of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Oncology Research: Used in the development of kinase inhibitors and other targeted cancer therapies due to its privileged scaffold.
• CNS Drug Discovery: Serves as a core structure for compounds designed to cross the blood-brain barrier for treating neurological disorders.
• Agrochemical Synthesis: Employed in research for creating new active ingredients with specific biological activity.
• Material Science Research: Investigated as a building block for organic electronic materials and specialty polymers.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	Methyl 3-Amino-Thieno[3,2-B]Pyridine-2-Carboxylate
CAS No.	171179-86-5
Molecular Formula	C9H8N2O2S
Molecular Weight	208.24 g/mol
Synonyms	Methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate; 3-Amino-thieno[3,2-b]pyridine-2-carboxylic acid methyl ester; Thieno[3,2-b]pyridine-2-carboxylic acid, 3-amino-, methyl ester; Methyl 3-amino-2-thieno[3,2-b]pyridinecarboxylate; 171179-86-5; CAS 171179-86-5
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-Thieno[3,2-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.