Description

tert-Butyl 7-Nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate is a high-purity, protected heterocyclic amine building block of significant importance in modern synthetic organic chemistry. This compound serves as a critical synthetic intermediate, enabling the controlled construction of complex nitrogen-containing molecular frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its nitrogen-rich heterocyclic structure.
• Organic Synthesis Building Block: The tert-butyloxycarbonyl (Boc) protecting group allows for selective reactions, making it valuable for multi-step synthesis of complex organic molecules.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials with specific electronic or binding properties.
• Academic & R&D Laboratories: A standard reagent for methodological development and exploration of new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 7-Nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS No.	171049-42-6
Molecular Formula	C₁₄H₁₈N₂O₄
Molecular Weight	278.31 g/mol
Synonyms	Boc-7-Nitro-1,2,3,4-tetrahydroisoquinoline; 2-(tert-Butoxycarbonyl)-7-nitro-1,2,3,4-tetrahydroisoquinoline; 7-Nitro-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester; tert-Butyl 7-nitro-1,2,3,4-tetrahydroisoquinoline-2-carboxylate; 7-Nitro-Boc-THIQ; 171049-42-6; 2-Boc-7-nitro-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.