Description

(4-Bromo-1,2-Phenylene)Dimethanol is a versatile brominated aromatic diol derivative, serving as a critical bifunctional building block in advanced organic synthesis. Its value lies in providing both a bromine substituent for cross-coupling reactions and two hydroxymethyl groups for polymerization or further functionalization, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries who require high-purity intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the bromine atom facilitates the introduction of other heterocyclic or aromatic systems.
• Ligand and Catalyst Preparation: Serves as a backbone for creating chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or chain extender in the production of specialty polyesters, polyurethanes, and epoxy resins, imparting specific thermal or mechanical properties.
• Material Science Research: Employed in the development of organic electronic materials, such as hole-transport layers or components for OLEDs.
• Cross-Coupling Reactions: The bromine site is ideal for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	(4-Bromo-1,2-Phenylene)Dimethanol
CAS No.	171011-37-3
Molecular Formula	C8H9BrO2
Molecular Weight	217.06 g/mol
Synonyms	4-Bromobenzene-1,2-dimethanol; 4-Bromo-1,2-bis(hydroxymethyl)benzene; 1,2-Bis(hydroxymethyl)-4-bromobenzene; 4-Bromophthalyl Alcohol; 4-Bromo-o-xylene-α,α'-diol; (4-Bromo-1,2-phenylene)bis(methanol); 4-Bromobenzene-1,2-diyldimethanol
EINECS	Contact for details

Quality Control

Our (4-Bromo-1,2-Phenylene)Dimethanol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production facilities and processes are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	105 - 110 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.