Description

4-tert-Butyl-2-(Chloromethyl)-1,3-Thiazole Hydrochloride is a high-purity, functionalized thiazole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites, the chloromethyl group and the thiazole ring, which enable its use in constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the thiazole moiety imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in catalytic systems and coordination chemistry.
• Material Science Research: Employed in the synthesis of functional organic materials, including polymers and liquid crystals with tailored electronic properties.
• Chemical Biology Probes: Useful for creating molecular probes and tags due to its reactive handles, facilitating bioconjugation and labeling studies.

Basic Information

Product Name	4-tert-Butyl-2-(Chloromethyl)-1,3-Thiazole Hydrochloride
CAS No.	170881-59-1
Molecular Formula	C8H13Cl2NS
Molecular Weight	226.16 g/mol
Synonyms	2-(Chloromethyl)-4-(1,1-dimethylethyl)-1,3-thiazole Hydrochloride; 4-tert-Butyl-2-(chloromethyl)thiazole Hydrochloride; 4-(tert-Butyl)-2-(chloromethyl)thiazole HCl; 1,3-Thiazole, 4-(1,1-dimethylethyl)-2-(chloromethyl)-, hydrochloride; 4-tert-Butyl-2-chloromethylthiazole Hydrochloride
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-2-(Chloromethyl)-1,3-Thiazole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.