Description

Fmoc-2-Piperidylmethanol CAS NO 170867-95-5 is a high-purity, protected amino alcohol building block essential for advanced organic synthesis. This compound is critical for the efficient and controlled construction of complex molecules, particularly in the field of peptide and peptidomimetic chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for introducing the 2-(hydroxymethyl)piperidine moiety into peptide chains, enabling the creation of novel peptide-based therapeutics and research tools.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates targeting neurological and metabolic disorders.
• Peptidomimetic Design: Used to create non-natural peptide analogs with enhanced stability, bioavailability, and biological activity for medicinal chemistry programs.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening to identify new lead compounds.
• Bioconjugation: The hydroxyl group provides a handle for linking peptides or other molecules to carriers, labels, or solid supports.
• Academic & Industrial Research: A fundamental reagent for investigating new synthetic methodologies and studying structure-activity relationships (SAR).

Basic Information

Product Name	Fmoc-2-Piperidylmethanol
CAS No.	170867-95-5
Molecular Formula	C₂₁H₂₃NO₃
Molecular Weight	337.41 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-(hydroxymethyl)piperidine; 2-[(Fmoc-amino)methyl]piperidine; 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)piperidine; Fmoc-2-piperidinemethanol; 2-(Hydroxymethyl)-1-piperidinecarboxylic acid 9H-fluoren-9-ylmethyl ester; 1-Fmoc-2-piperidinemethanol; (2-Piperidyl)methanol, N-Fmoc derivative; Fmoc-Amp(2)-OH (commonly used abbreviation)
EINECS	Contact for details

Quality Control

Our Fmoc-2-Piperidylmethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee batch-to-batch consistency and traceability, meeting the stringent requirements of research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.