Description

(Rs)-1-Amino-5-Phosphonoindan-1-Carboxylic Acid is a high-purity, chiral indane derivative that serves as a sophisticated building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates both amino, phosphono, and carboxylic acid functional groups on a fused ring system, enabling precise molecular design. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in neurological and metabolic disorder pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides, pesticides, and plant growth regulators that require specific stereochemistry.
• Chemical Biology Probe: Serves as a scaffold or precursor for designing molecular probes to study enzyme mechanisms and protein interactions.
• Ligand Synthesis: Utilized in the preparation of complex chelating ligands for catalysis and metal ion sequestration.
• Peptidomimetics: Acts as a constrained, non-proteinogenic amino acid analog in the design of peptide-like molecules with enhanced stability.
• Academic & Institutional Research: Employed in universities and research institutes for methodological development in asymmetric synthesis and medicinal chemistry.

Basic Information

Product Name	(Rs)-1-Amino-5-Phosphonoindan-1-Carboxylic Acid
CAS No.	170847-18-4
Molecular Formula	C10H12NO5P
Molecular Weight	257.18 g/mol
Synonyms	1-Amino-5-phosphonoindane-1-carboxylic acid; APICA; (RS)-APICA; 1-Aminoindane-1-carboxylic acid-5-phosphonic acid; 5-Phosphono-1-aminoindan-1-carboxylic acid; (±)-1-Amino-5-phosphonoindan-1-carboxylic acid; rac-1-Amino-5-phosphonoindan-1-carboxylic acid; Indane-1-amino-5-phosphono-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our (Rs)-1-Amino-5-Phosphonoindan-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral composition is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Racemic mixture (RS)
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.