Description

n-[5-[2-[Bis[4-(Difluoromethoxy)Phenyl]Methylamino]-1(R)-Hydroxyethyl]-2-Hydroxyphenyl]Methanesulfonamide is a sophisticated chiral organic compound featuring a methanesulfonamide group and difluoromethoxy-substituted aromatic rings. This molecule is of significant interest in advanced pharmaceutical research and development due to its potential as a key intermediate or active pharmaceutical ingredient (API) precursor. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly those targeting complex biochemical pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• Biochemical Research: Used as a reference standard or probe compound in pharmacological studies to investigate receptor interactions and enzyme inhibition.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing reaction conditions for the production of target drug candidates.
• Analytical Standard: Provides a high-purity standard for method development and validation in quality control laboratories using techniques like HPLC and LC-MS.

Basic Information

Product Name	n-[5-[2-[Bis[4-(Difluoromethoxy)Phenyl]Methylamino]-1(R)-Hydroxyethyl]-2-Hydroxyphenyl]Methanesulfonamide
CAS No.	170686-12-1
Molecular Formula	C25H27F4N2O6S
Molecular Weight	559.56 g/mol
Synonyms	Methanesulfonamide, N-[5-[(1R)-2-[bis[4-(difluoromethoxy)phenyl]methylamino]-1-hydroxyethyl]-2-hydroxyphenyl]-; (R)-N-(5-(2-(Bis(4-(difluoromethoxy)phenyl)(methyl)amino)-1-hydroxyethyl)-2-hydroxyphenyl)methanesulfonamide; UNII-8KQ3J5F2Q2; 8KQ3J5F2Q2; CHEMBL3183450; BDBM50389357; AKOS025147065; ZINC000003869756
EINECS	Contact for details

Quality Control

Our n-[5-[2-[Bis[4-(Difluoromethoxy)Phenyl]Methylamino]-1(R)-Hydroxyethyl]-2-Hydroxyphenyl]Methanesulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing results from HPLC, NMR, and chiral purity assays to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.