Description

Methyl 1-Chloro-4-Methoxyisoquinoline-3-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique isoquinoline scaffold, which serves as a critical intermediate in the development of novel pharmaceutical compounds and agrochemicals. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoquinoline moiety.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, and photoactive materials for electronic applications.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities (NCEs).
• Custom Synthesis: An ideal starting material for contract manufacturing organizations (CMOs) performing bespoke synthesis for client-specific projects.

Basic Information

Product Name	Methyl 1-Chloro-4-Methoxyisoquinoline-3-Carboxylate
CAS No.	170621-96-2
Molecular Formula	C12H10ClNO3
Molecular Weight	251.66 g/mol
Synonyms	1-Chloro-4-methoxyisoquinoline-3-carboxylic acid methyl ester; Methyl 1-chloro-4-methoxy-3-isoquinolinecarboxylate; 3-Isoquinolinecarboxylic acid, 1-chloro-4-methoxy-, methyl ester; 1-Chloro-4-methoxyisoquinoline-3-carboxylate methyl ester; 170621-96-2; Methyl 1-chloro-4-methoxy-3-isoquinolinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 1-Chloro-4-Methoxyisoquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.