Description

(S)-n-(Ethoxycarbonyl)-α-Methyl-D-Tryptophan Methyl Ester CAS NO 170458-98-7 is a high-purity, non-natural amino acid derivative, specifically an enantiomerically pure tryptophan analog. This compound serves as a critical chiral building block and intermediate in advanced pharmaceutical synthesis, enabling the development of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in the development of peptidomimetics, protease inhibitors, and other bioactive molecules where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorders.
• Peptidomimetic Synthesis: Used to incorporate modified tryptophan residues into peptide analogs to enhance stability, bioavailability, and receptor selectivity.
• Protease Inhibitor Development: Serves as a core structural component in the design of inhibitors targeting specific enzymes.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in stereoselective chemical transformations to construct complex molecular architectures.
• Biochemical Research: Utilized in academic and industrial R&D for studying enzyme-substrate interactions and structure-activity relationships (SAR).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in chromatographic analysis.

Basic Information

Product Name	(S)-n-(Ethoxycarbonyl)-α-Methyl-D-Tryptophan Methyl Ester
CAS No.	170458-98-7
Molecular Formula	C₁₇H₂₀N₂O₄
Molecular Weight	316.35 g/mol
Synonyms	(S)-N-[(Ethoxycarbonyl)-α-methyl-D-tryptophan] methyl ester; Methyl (2S)-3-(1H-indol-3-yl)-2-{[(ethoxycarbonyl)amino]methyl}-2-methylpropanoate; D-Tryptophan, N-[(ethoxycarbonyl)-α-methyl-, methyl ester, (S)-; (S)-α-Methyl-N-(ethoxycarbonyl)-D-tryptophan methyl ester; (S)-N-Carbethoxy-α-methyl-D-tryptophan methyl ester; N-Carbethoxy-α-methyl-D-tryptophan methyl ester (S-isomer); (S)-N-(Ethoxycarbonyl)-α-methyl-D-tryptophan methyl ester
EINECS	Contact for details

Quality Control

Our (S)-n-(Ethoxycarbonyl)-α-Methyl-D-Tryptophan Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards suitable for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.