Description

tert-Butyl 5-(Benzyloxy)-1H-Indole-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its indole core protected with tert-butyloxycarbonyl (Boc) and benzyloxy functional groups. This compound is of significant value in organic synthesis, serving as a critical building block for constructing complex molecules with precise stereochemistry and functionality. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and bioactive molecules.
• Organic Synthesis Building Block: Used for introducing protected indole scaffolds in medicinal chemistry and process research.
• Research & Development (R&D): Essential for academic and industrial research in heterocyclic chemistry and new synthetic methodology development.
• API Development: Employed in the route scouting and optimization for potential new therapeutic agents.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	tert-Butyl 5-(Benzyloxy)-1H-Indole-1-Carboxylate
CAS No.	170147-29-2
Molecular Formula	C20H21NO3
Molecular Weight	323.39 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 5-(phenylmethoxy)-, 1,1-dimethylethyl ester; 5-Benzyloxy-1H-indole-1-carboxylic acid tert-butyl ester; Boc-5-benzyloxyindole; tert-Butyl 5-benzyloxy-1H-indole-1-carboxylate; 1-Boc-5-benzyloxyindole; 5-(Benzyloxy)indole-1-carboxylic Acid tert-Butyl Ester; N-Boc-5-benzyloxyindole
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-(Benzyloxy)-1H-Indole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.