Description

2-tert-Butyl 6-Methyl 3,4-Dihydroisoquinoline-2,6(1H)-Dicarboxylate is a high-purity, protected dihydroisoquinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in providing a versatile scaffold for constructing complex nitrogen-containing heterocycles, which are essential in modern pharmaceutical and agrochemical research. This compound is particularly sought after by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactive isoquinoline core structure.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds used in material science, dyes, and specialty polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis, including novel cyclization and functionalization reactions.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for target molecules in a GMP or non-GMP environment.

Basic Information

Product Name	2-tert-Butyl 6-Methyl 3,4-Dihydroisoquinoline-2,6(1H)-Dicarboxylate
CAS No.	170097-66-2
Molecular Formula	C17H23NO4
Molecular Weight	305.37 g/mol
Synonyms	2-(tert-Butoxycarbonyl)-6-(methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline; 2-tert-Butyl 6-methyl 1,2,3,4-tetrahydroisoquinoline-2,6-dicarboxylate; 2-Boc-6-COOMe-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydroisoquinoline-2,6-dicarboxylic acid 2-tert-butyl 6-methyl ester; 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydro-6-isoquinolinecarboxylic acid methyl ester; 2-tert-Butoxycarbonyl-6-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline; 2-tert-Butyl 6-methyl ester of 3,4-dihydroisoquinoline-2,6(1H)-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl 6-Methyl 3,4-Dihydroisoquinoline-2,6(1H)-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support customer audits and can supply material with custom purity grades to meet specific project requirements, from research to pilot plant scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.