Description

2H-Benzimidazole-2-Thione,4,6-Difluoro-1,3-Dihydro-(9Ci) is a specialized heterocyclic organic compound featuring a benzimidazole core substituted with fluorine atoms and a thione group, offering unique reactivity and electronic properties. This high-purity intermediate is critical for advanced research and development in pharmaceutical and agrochemical synthesis, where precise molecular architecture is paramount. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Used in the development of next-generation fungicides, herbicides, and plant growth regulators, leveraging the fluorine-substituted benzimidazole scaffold.
• Material Science Research: Serves as a precursor for organic electronic materials, ligands for catalysis, and functional dyes due to its electron-rich structure.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies, given its ability to interact with biological thiols.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	2H-Benzimidazole-2-Thione,4,6-Difluoro-1,3-Dihydro-(9Ci)
CAS No.	169905-05-9
Molecular Formula	C7H4F2N2S
Molecular Weight	186.18 g/mol
Synonyms	4,6-Difluoro-1,3-dihydro-2H-benzimidazole-2-thione; 4,6-Difluoro-2-mercaptobenzimidazole; 4,6-Difluorobenzimidazole-2-thiol; 4,6-Difluoro-2-benzimidazolethione; 4,6-Difluoro-1H-benzimidazole-2(3H)-thione; 2-Mercapto-4,6-difluorobenzimidazole; 169905-05-9
EINECS	Contact for details

Quality Control

Our 2H-Benzimidazole-2-Thione,4,6-Difluoro-1,3-Dihydro-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.