Description

4-(Trifluoromethoxy)Thiophenol is a specialized organosulfur compound featuring a thiol group and a trifluoromethoxy substituent on the aromatic ring. This structure is highly valued for its role as a versatile building block in advanced chemical synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those requiring bioisosteric replacement or modulation of lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group can improve metabolic stability and activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of monomers and functional agents for advanced polymers and specialty materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and constructing complex sulfur-containing heterocycles.

Basic Information

Product Name	4-(Trifluoromethoxy)Thiophenol
CAS No.	169685-29-4
Molecular Formula	C7H5F3OS
Molecular Weight	194.17 g/mol
Synonyms	p-(Trifluoromethoxy)benzenethiol; 4-(Trifluoromethoxy)benzenethiol; 1-(Trifluoromethoxy)-4-mercaptobenzene; α,α,α-Trifluoro-p-cresol Mercaptan; 4-Mercaptophenyl trifluoromethyl ether; (4-Mercaptophenyl) trifluoromethyl ether; 4-Trifluoromethoxy thiophenol
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Thiophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.