Description

5-Chloro-6-Fluoro-1H-Indole is a high-purity halogenated indole derivative, a crucial building block in advanced organic synthesis. Its unique molecular structure, featuring both chloro and fluoro substituents, makes it an indispensable intermediate for creating complex molecules with targeted biological activity. This compound is primarily sought after by pharmaceutical and agrochemical research and development teams for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogen atoms can enhance bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Biochemical Probe Development: Employed in medicinal chemistry to create molecular probes for studying enzyme mechanisms and receptor interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Chloro-6-Fluoro-1H-Indole
CAS No.	169674-57-1
Molecular Formula	C8H5ClFN
Molecular Weight	169.58 g/mol
Synonyms	5-Chloro-6-fluoroindole; 6-Fluoro-5-chloro-1H-indole; 1H-Indole, 5-chloro-6-fluoro-; 5-Chloro-6-fluoro-1H-indole; 169674-57-1; 5-Chloro-6-fluoroindole; 6-Fluoro-5-chloroindole
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Fluoro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.