Description

5,6-Difluoroindole-2-Carboxylic Acid is a high-purity fluorinated indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in modulating the biological activity and physicochemical properties of target molecules, particularly in pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in developing new generation herbicides and pesticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical assays and diagnostic development.
• Fluorine Chemistry: A valuable substrate for studying structure-activity relationships (SAR) due to the strategic difluoro substitution on the indole core.

Basic Information

Product Name	5,6-Difluoroindole-2-Carboxylic Acid
CAS No.	169674-35-5
Molecular Formula	C9H5F2NO2
Molecular Weight	197.14 g/mol
Synonyms	2-Carboxy-5,6-difluoroindole; 5,6-Difluoro-1H-indole-2-carboxylic acid; 5,6-Difluoroindole-2-carboxylate; 169674-35-5; 5,6-Difluoro-2-indolecarboxylic acid; Difluoroindolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5,6-Difluoroindole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.