Description

4-Chloro-5-Fluoroindole is a high-purity halogenated indole derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which enables the introduction of both chloro and fluoro substituents onto the indole scaffold, a key modification for fine-tuning the biological activity and physicochemical properties of target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the indole core provides specific biological activity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLEDs and conductive polymers, due to its electron-rich heterocyclic structure.
• Biochemical Probe Development: Employed in medicinal chemistry to create molecular probes for studying enzyme mechanisms and receptor interactions.
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and CROs (Contract Research Organizations) exploring novel heterocyclic compounds.

Basic Information

Product Name	4-Chloro-5-Fluoroindole
CAS No.	169674-02-6
Molecular Formula	C8H5ClFN
Molecular Weight	169.58 g/mol
Synonyms	5-Fluoro-4-chloroindole; 4-Chloro-5-fluoro-1H-indole; 1H-Indole, 4-chloro-5-fluoro-; 4-Chloro-5-fluoroindole; 5-Fluoro-4-chloro-1H-indole
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-5-Fluoroindole is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.