Description

Deracoxib is a highly selective non-steroidal anti-inflammatory drug (NSAID) belonging to the coxib class, specifically designed to target the COX-2 enzyme. This targeted action makes it a valuable active pharmaceutical ingredient (API) for managing pain and inflammation with a potentially improved gastrointestinal safety profile compared to non-selective NSAIDs. It is primarily utilized by pharmaceutical manufacturers in the veterinary and human healthcare sectors for the formulation of prescription medications.

Application

• Veterinary Pharmaceuticals: As the primary active ingredient in prescription medications for the control of post-operative pain and inflammation in dogs, particularly following orthopedic surgery.
• Human Pharmaceutical R&D: Serves as a key reference standard and intermediate in research and development programs focused on novel COX-2 inhibitor therapies.
• Analytical Standard: Used as a certified reference material (CRM) in quality control laboratories for method development, validation, and assay of finished pharmaceutical products.
• API Manufacturing: Employed by contract manufacturing organizations (CMOs) for the production of finished dosage forms such as chewable tablets.
• Academic & Institutional Research: Utilized in pharmacological studies to investigate the mechanisms of cyclooxygenase inhibition and inflammatory pathways.

Basic Information

Product Name	Deracoxib
CAS No.	169590-41-4
Molecular Formula	C13H13N3O2S2
Molecular Weight	307.39 g/mol
Synonyms	4-[3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzenesulfonamide; Deramaxx; SC-59046; UNII-7P0K26EG5I; COX-2 Inhibitor SC-59046; 1H-Pyrazole-1-benzenesulfonamide derivative
EINECS	Contact for details

Quality Control

Our Deracoxib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for identity, purity, and impurities. We support compliance with cGMP and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.