Description

(+/-)-Amphetamine-D10 CAS NO 169565-17-7 is a deuterated analog of amphetamine, where ten hydrogen atoms are replaced with deuterium, serving as a crucial stable isotope-labeled internal standard. This compound is essential for ensuring the accuracy and reliability of quantitative analytical methods, particularly in forensic and clinical toxicology. It is primarily used by analytical laboratories, forensic science institutions, and pharmaceutical R&D departments for precise mass spectrometry-based analysis.

Application

• Quantitative Internal Standard in LC-MS/MS and GC-MS: Used for the accurate quantification of amphetamine and related substances in complex biological matrices like urine, blood, and plasma.
• Forensic Toxicology and Drug Testing: Critical for method development and validation in workplace drug screening, post-mortem analysis, and DUID (Driving Under the Influence of Drugs) investigations.
• Pharmacokinetic and Metabolism Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in pharmaceutical research.
• Reference Material for Method Calibration: Serves as a certified reference material to calibrate analytical instruments and ensure method compliance with regulatory guidelines (e.g., SAMHSA, WADA).
• Quality Control in Pharmaceutical Analysis: Employed in the analysis of pharmaceutical formulations and the monitoring of synthetic pathways for amphetamine-based active pharmaceutical ingredients (APIs).
• Research on Neurotransmitter Systems: Used in neuroscience research as a tool to study the mechanisms of amphetamine and its effects on dopamine and norepinephrine systems.

Basic Information

Product Name	(+/-)-Amphetamine-D10
CAS No.	169565-17-7
Molecular Formula	C9D10N
Molecular Weight	144.25 g/mol
Synonyms	(±)-Amphetamine-d10; DL-Amphetamine-d10; 1-Phenyl-2-aminopropane-d10; α-Methylphenethylamine-d10; Benzenethanamine, α-methyl-d10; Racemic Amphetamine-d10; Amphetamine Deuterated Standard; Amphetamine-d10 (Internal Standard)
EINECS	Contact for details

Quality Control

Our (+/-)-Amphetamine-D10 is manufactured under strict quality systems to ensure the highest isotopic purity and chemical integrity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (Atom % D), chemical purity (by HPLC), and confirmation of structure (by NMR and MS). We support compliance with ISO 17034 for reference material producers and relevant forensic laboratory accreditation standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or CoA. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.