Description

3-Hydroxymethyl-5-Methyl-N(4-Chlorophenyl)-Pyrazole is a specialized pyrazole derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both hydroxymethyl and chlorophenyl substituents, makes it a critical intermediate for constructing more complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection agent development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole ring.
• Ligand and Catalyst Development: Used in coordination chemistry to create specialized ligands for metal catalysts used in asymmetric synthesis and polymerization reactions.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or optical properties.
• Chemical Biology Probes: Employed in academic and industrial research to develop molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	3-Hydroxymethyl-5-Methyl-N(4-Chlorophenyl)-Pyrazole
CAS No.	169547-92-6
Molecular Formula	C11H11ClN2O
Molecular Weight	222.67 g/mol
Synonyms	1-(4-Chlorophenyl)-5-methyl-1H-pyrazole-3-methanol; 3-(Hydroxymethyl)-5-methyl-1-(4-chlorophenyl)-1H-pyrazole; 5-Methyl-1-(4-chlorophenyl)-1H-pyrazole-3-methanol; N-(4-Chlorophenyl)-5-methyl-1H-pyrazole-3-methanol; 1-(p-Chlorophenyl)-5-methylpyrazole-3-methanol; 169547-92-6 (CAS Registry Number); Pyrazole derivative, 3-hydroxymethyl-5-methyl-N-(4-chlorophenyl)-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of 3-Hydroxymethyl-5-Methyl-N(4-Chlorophenyl)-Pyrazole is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system is designed to support cGMP compliance for pharmaceutical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.